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Vaccination with short-term-cultured autologous PBMCs efficiently activated STLV-1-specific CTLs in naturally STLV-1-infected Japanese monkeys with impaired CTL responses

A small proportion of human T-cell leukemia virus type-1 (HTLV-1)-infected individuals develop adult T-cell leukemia/lymphoma, a chemotherapy-resistant lymphoproliferative disease with a poor prognosis. HTLV-1-specific cytotoxic T lymphocytes (CTLs), potential anti-tumor/virus effectors, are impaire...

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Detalles Bibliográficos
Autores principales:	Hasegawa, Atsuhiko, Murata, Megumi, Fujikawa, Tomoka, Katagiri, Kuniko, Nagano, Yoshiko, Masuda, Takao, Kuramitsu, Madoka, Nakajima, Shinsuke, Fujisawa, Jun-ichi, Okuma, Kazu, Grover, Poonam, Kidiga, Maureen, Akari, Hirofumi, Kannagi, Mari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928132/ https://www.ncbi.nlm.nih.gov/pubmed/36730466 http://dx.doi.org/10.1371/journal.ppat.1011104

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