Targeting RNA:protein interactions with an integrative approach leads to the identification of potent YBX1 inhibitors

RNA-protein interactions (RPIs) are promising targets for developing new molecules of therapeutic interest. Nevertheless, challenges arise from the lack of methods and feedback between computational and experimental techniques during the drug discovery process. Here, we tackle these challenges by de...

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Detalles Bibliográficos
Autores principales: El Hage, Krystel, Babault, Nicolas, Maciejak, Olek, Desforges, Bénédicte, Craveur, Pierrick, Steiner, Emilie, Rengifo-Gonzalez, Juan Carlos, Henrie, Hélène, Clement, Marie-Jeanne, Joshi, Vandana, Bouhss, Ahmed, Wang, Liya, Bauvais, Cyril, Pastré, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928419/
https://www.ncbi.nlm.nih.gov/pubmed/36651723
http://dx.doi.org/10.7554/eLife.80387

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