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Polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: A case report
BACKGROUND: Although fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is widely used for diagnosis and follow-up of large sized vessel vasculitis, it is still not widely used for small to medium sized vessel vasculitis. CASE SUMMARY: This is the case of a 68-year-old...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928714/ https://www.ncbi.nlm.nih.gov/pubmed/36818617 http://dx.doi.org/10.12998/wjcc.v11.i4.918 |
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author | Kang, Ji-Hyoun Kim, Jahae |
author_facet | Kang, Ji-Hyoun Kim, Jahae |
author_sort | Kang, Ji-Hyoun |
collection | PubMed |
description | BACKGROUND: Although fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is widely used for diagnosis and follow-up of large sized vessel vasculitis, it is still not widely used for small to medium sized vessel vasculitis. CASE SUMMARY: This is the case of a 68-year-old male who presented at the emergency department complaining of fever, myalgia, and bilateral leg pain of over two weeks duration, with elevated levels of C-reactive protein. He was subsequently admitted and despite the absence of clinically significant findings, the patient continued to exhibit recurrent fever. A fever of unknown origin workup, which included imaging studies using FDG-PET/CT, revealed vasculitis involving small to medium-sized vessels of both lower extremities, demonstrated by linear hypermetabolism throughout the leg muscles. The patient was treated with methylprednisolone and methotrexate after diagnosis leading to the gradual resolution of the patient’s symptoms. Three weeks later, a follow-up FDG-PET/CT was performed. Previously hypermetabolic vessels were markedly improved. CONCLUSION: Our case report demonstrated that FDG-PET/CT has tremendous potential to detect medium-sized vessel inflammation; it can also play a crucial role in prognosticating outcomes and monitoring therapeutic efficacy. |
format | Online Article Text |
id | pubmed-9928714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-99287142023-02-16 Polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: A case report Kang, Ji-Hyoun Kim, Jahae World J Clin Cases Case Report BACKGROUND: Although fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is widely used for diagnosis and follow-up of large sized vessel vasculitis, it is still not widely used for small to medium sized vessel vasculitis. CASE SUMMARY: This is the case of a 68-year-old male who presented at the emergency department complaining of fever, myalgia, and bilateral leg pain of over two weeks duration, with elevated levels of C-reactive protein. He was subsequently admitted and despite the absence of clinically significant findings, the patient continued to exhibit recurrent fever. A fever of unknown origin workup, which included imaging studies using FDG-PET/CT, revealed vasculitis involving small to medium-sized vessels of both lower extremities, demonstrated by linear hypermetabolism throughout the leg muscles. The patient was treated with methylprednisolone and methotrexate after diagnosis leading to the gradual resolution of the patient’s symptoms. Three weeks later, a follow-up FDG-PET/CT was performed. Previously hypermetabolic vessels were markedly improved. CONCLUSION: Our case report demonstrated that FDG-PET/CT has tremendous potential to detect medium-sized vessel inflammation; it can also play a crucial role in prognosticating outcomes and monitoring therapeutic efficacy. Baishideng Publishing Group Inc 2023-02-06 2023-02-06 /pmc/articles/PMC9928714/ /pubmed/36818617 http://dx.doi.org/10.12998/wjcc.v11.i4.918 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Kang, Ji-Hyoun Kim, Jahae Polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: A case report |
title | Polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: A case report |
title_full | Polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: A case report |
title_fullStr | Polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: A case report |
title_full_unstemmed | Polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: A case report |
title_short | Polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: A case report |
title_sort | polyarteritis nodosa presenting as leg pain with resolution of positron emission tomography-images: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928714/ https://www.ncbi.nlm.nih.gov/pubmed/36818617 http://dx.doi.org/10.12998/wjcc.v11.i4.918 |
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