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Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders

Through serendipity, we observed an apparent synergy between adopting a ketogenic diet and receiving ketamine infusions that led to complete and durable remission in two patients with chronic enduring anorexia nervosa. Both patients had struggled with the disorder for over a decade. We offer a hypot...

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Detalles Bibliográficos
Autores principales: Scolnick, Barbara, Beckwith, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928830/
https://www.ncbi.nlm.nih.gov/pubmed/36788151
http://dx.doi.org/10.1007/s40519-023-01528-5
Descripción
Sumario:Through serendipity, we observed an apparent synergy between adopting a ketogenic diet and receiving ketamine infusions that led to complete and durable remission in two patients with chronic enduring anorexia nervosa. Both patients had struggled with the disorder for over a decade. We offer a hypothesis, based on glutamate to explain this synergy, and hope it stimulates further research.