Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders

Through serendipity, we observed an apparent synergy between adopting a ketogenic diet and receiving ketamine infusions that led to complete and durable remission in two patients with chronic enduring anorexia nervosa. Both patients had struggled with the disorder for over a decade. We offer a hypot...

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Detalles Bibliográficos
Autores principales: Scolnick, Barbara, Beckwith, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928830/
https://www.ncbi.nlm.nih.gov/pubmed/36788151
http://dx.doi.org/10.1007/s40519-023-01528-5
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author Scolnick, Barbara
Beckwith, Caroline
author_facet Scolnick, Barbara
Beckwith, Caroline
author_sort Scolnick, Barbara
collection PubMed
description Through serendipity, we observed an apparent synergy between adopting a ketogenic diet and receiving ketamine infusions that led to complete and durable remission in two patients with chronic enduring anorexia nervosa. Both patients had struggled with the disorder for over a decade. We offer a hypothesis, based on glutamate to explain this synergy, and hope it stimulates further research.
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spelling pubmed-99288302023-02-16 Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders Scolnick, Barbara Beckwith, Caroline Eat Weight Disord Correspondence Through serendipity, we observed an apparent synergy between adopting a ketogenic diet and receiving ketamine infusions that led to complete and durable remission in two patients with chronic enduring anorexia nervosa. Both patients had struggled with the disorder for over a decade. We offer a hypothesis, based on glutamate to explain this synergy, and hope it stimulates further research. Springer International Publishing 2023-02-14 2023 /pmc/articles/PMC9928830/ /pubmed/36788151 http://dx.doi.org/10.1007/s40519-023-01528-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Correspondence
Scolnick, Barbara
Beckwith, Caroline
Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders
title Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders
title_full Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders
title_fullStr Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders
title_full_unstemmed Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders
title_short Synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders
title_sort synergy between ketamine and ketogenic diet in anorexia nervosa, and other neurobehavioral disorders
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928830/
https://www.ncbi.nlm.nih.gov/pubmed/36788151
http://dx.doi.org/10.1007/s40519-023-01528-5
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