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In vitro assessment of Neuronal PAS domain 2 mitigating compounds for scarless wound healing
BACKGROUND: The core circadian gene Neuronal PAS domain 2 (NPAS2) is expressed in dermal fibroblasts and has been shown to play a critical role in regulating collagen synthesis during wound healing. We have performed high throughput drug screening to identify genes responsible for downregulation of...
Autores principales: | Clements, Adam, Shibuya, Yoichiro, Hokugo, Akishige, Brooks, Zachary, Roca, Yvonne, Kondo, Takeru, Nishimura, Ichiro, Jarrahy, Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928850/ https://www.ncbi.nlm.nih.gov/pubmed/36816724 http://dx.doi.org/10.3389/fmed.2022.1014763 |
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