Cargando…

NAMPT and NAPRT serum levels predict response to anti-TNF therapy in inflammatory bowel disease

BACKGROUND: Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinic acid phosphoribosyl transferase (NAPRT) are key intracellular enzymes that participate in the biosynthesis on NAD but have also been shown to be released as proinflammatory cytokines. A number of reports have shown that circula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Colombo, Giorgia, Caviglia, Gian Paolo, Ravera, Alberto, Tribocco, Elisa, Frara, Simone, Rosso, Chiara, Travelli, Cristina, Genazzani, Armando A., Ribaldone, Davide Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9928959/ https://www.ncbi.nlm.nih.gov/pubmed/36817780 http://dx.doi.org/10.3389/fmed.2023.1116862

Ejemplares similares

The Predictive Role of Extracellular NAPRT for the Detection of Advanced Fibrosis in Biopsy-Proven Non-Alcoholic Fatty Liver Disease
por: Armandi, Angelo, et al.
Publicado: (2023)

Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy
por: Galli, Ubaldina, et al.
Publicado: (2020)

NAMPT and NAPRT: Two Metabolic Enzymes With Key Roles in Inflammation
por: Audrito, Valentina, et al.
Publicado: (2020)

Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy
por: Caviglia, Gian Paolo, et al.
Publicado: (2023)

The Cytokine Nicotinamide Phosphoribosyltransferase (eNAMPT; PBEF; Visfatin) Acts as a Natural Antagonist of C-C Chemokine Receptor Type 5 (CCR5)
por: Torretta, Simone, et al.
Publicado: (2020)

NAPRT, but Not NAMPT, Provides Additional Support for NAD Synthesis in Esophageal Precancerous Lesions
por: Wang, Niannian, et al.
Publicado: (2022)

Inflammatory Bowel Disease: Emerging Therapies and Future Treatment Strategies
por: Bretto, Elisabetta, et al.
Publicado: (2023)

The NAMPT inhibitor FK866 reverts the damage in spinal cord injury
por: Esposito, Emanuela, et al.
Publicado: (2012)

Switching from Biosimilar to Biosimilar Adalimumab, Including Multiple Switching, in Crohn’s Disease: A Prospective Study
por: Ribaldone, Davide Giuseppe, et al.
Publicado: (2021)

NAMPT and NAPRT1: novel polymorphisms and distribution of variants between normal tissues and tumor samples
por: Duarte-Pereira, Sara, et al.
Publicado: (2014)

PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma
por: Fons, Nathan R., et al.
Publicado: (2019)

NAMPT and NAPRT, Key Enzymes in NAD Salvage Synthesis Pathway, Are of Negative Prognostic Value in Colorectal Cancer
por: Li, Xiao-qin, et al.
Publicado: (2019)

Extracellular nicotinamide phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
por: Colombo, Giorgia, et al.
Publicado: (2022)

Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer
por: Travelli, Cristina, et al.
Publicado: (2023)

Efficacy and Safety of Adalimumab Biosimilar GP2017 in Patients with Inflammatory Bowel Disease
por: Vernero, Marta, et al.
Publicado: (2023)

Risk Factors of Urothelial Cancer in Inflammatory Bowel Disease
por: Caviglia, Gian Paolo, et al.
Publicado: (2021)

Inflammatory Bowel Disease Nurse—Practical Messages
por: Rosso, Chiara, et al.
Publicado: (2021)

The Impact of Dysmetabolic Sarcopenia Among Insulin Sensitive Tissues: A Narrative Review
por: Armandi, Angelo, et al.
Publicado: (2021)

Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy
por: Kim, Minjee, et al.
Publicado: (2023)

Inflammatory Bowel Disease: Role of Vagus Nerve Stimulation
por: Fornaro, Riccardo, et al.
Publicado: (2022)

Hepatitis B Core-Related Antigen as Surrogate Biomarker of Intrahepatic Hepatitis B Virus Covalently-Closed-Circular DNA in Patients with Chronic Hepatitis B: A Meta-Analysis
por: Caviglia, Gian Paolo, et al.
Publicado: (2021)

Special Issue “Advances in Gastrointestinal and Liver Disease: From Physiological Mechanisms to Clinical Practice”
por: Caviglia, Gian Paolo, et al.
Publicado: (2022)

Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery
por: Ghanem, Moustafa S., et al.
Publicado: (2022)

Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy
por: Cole, Jonathan, et al.
Publicado: (2017)

Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors
por: Franco, Jorge, et al.
Publicado: (2022)

Insight Into Nicotinamide Adenine Dinucleotide Homeostasis as a Targetable Metabolic Pathway in Colorectal Cancer
por: Colombo, Giorgia, et al.
Publicado: (2021)

Data on metabolic stability, aqueous solubility and CYP inhibition of novel triazole-based nicotinamide phosphoribosyltransferase (NAMPT) inhibitors
por: Aprile, Silvio, et al.
Publicado: (2019)

Strategies for Helicobacter pylori eradication in the year 2020
por: Pellicano, Rinaldo, et al.
Publicado: (2020)

Incidence of Prostate Cancer in Inflammatory Bowel Disease: A Meta-Analysis
por: Carli, Edoardo, et al.
Publicado: (2020)

A Retrospective Experience of Helicobacter pylori Histology in a Large Sample of Subjects in Northern Italy
por: Ribaldone, Davide Giuseppe, et al.
Publicado: (2021)

Intestinal microbiota changes induced by TNF-inhibitors in IBD-related spondyloarthritis
por: Ditto, Maria Chiara, et al.
Publicado: (2021)

Predictive Factors of Surgical Recurrence in Patients with Crohn’s Disease on Long-Term Follow-Up: A Focus on Histology
por: Caviglia, Gian Paolo, et al.
Publicado: (2022)

Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors
por: Duarte-Pereira, Sara, et al.
Publicado: (2015)

Clinical Response and Changes of Cytokines and Zonulin Levels in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome Treated with Bifidobacterium Longum ES1 for 8 or 12 Weeks: A Preliminary Report
por: Caviglia, Gian Paolo, et al.
Publicado: (2020)

Properly Substituted Benzimidazoles as a New Promising Class of Nicotinate Phosphoribosyltransferase (NAPRT) Modulators
por: Baldassarri, Cecilia, et al.
Publicado: (2023)

Efficacy of a Preparation Based on Calcium Butyrate, Bifidobacterium bifidum, Bifidobacterium lactis, and Fructooligosaccharides in the Prevention of Relapse in Ulcerative Colitis: A Prospective Observational Study
por: Caviglia, Gian Paolo, et al.
Publicado: (2021)

NAPRT Expression Regulation Mechanisms: Novel Functions Predicted by a Bioinformatics Approach
por: Duarte-Pereira, Sara, et al.
Publicado: (2021)

On-Treatment Decrease of Serum Interleukin-6 as a Predictor of Clinical Response to Biologic Therapy in Patients with Inflammatory Bowel Diseases
por: Caviglia, Gian Paolo, et al.
Publicado: (2020)

Serum Interleukin-6 and -8 as Predictors of Response to Vedolizumab in Inflammatory Bowel Diseases
por: Bertani, Lorenzo, et al.
Publicado: (2020)

Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine
por: Grolla, Ambra A, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_qmpi4n7l93emkaa7931vut2b1s