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Robustness of a multivariate composite score when evaluating distress of animal models for gastrointestinal diseases

The fundament of an evidence-based severity assessment in laboratory animal science is reliable distress parameters. Many readouts are used to evaluate and determine animal distress and the severity of experimental procedures. Therefore, we analyzed four distinct parameters like the body weight, bur...

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Detalles Bibliográficos
Autores principales: Talbot, Steven R., Kumstel, Simone, Schulz, Benjamin, Tang, Guanglin, Abdelrahman, Ahmed, Seume, Nico, Wendt, Edgar H. U., Eichberg, Johanna, Häger, Christine, Bleich, André, Vollmar, Brigitte, Zechner, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929045/
https://www.ncbi.nlm.nih.gov/pubmed/36788346
http://dx.doi.org/10.1038/s41598-023-29623-8