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Robustness of a multivariate composite score when evaluating distress of animal models for gastrointestinal diseases
The fundament of an evidence-based severity assessment in laboratory animal science is reliable distress parameters. Many readouts are used to evaluate and determine animal distress and the severity of experimental procedures. Therefore, we analyzed four distinct parameters like the body weight, bur...
Autores principales: | Talbot, Steven R., Kumstel, Simone, Schulz, Benjamin, Tang, Guanglin, Abdelrahman, Ahmed, Seume, Nico, Wendt, Edgar H. U., Eichberg, Johanna, Häger, Christine, Bleich, André, Vollmar, Brigitte, Zechner, Dietmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929045/ https://www.ncbi.nlm.nih.gov/pubmed/36788346 http://dx.doi.org/10.1038/s41598-023-29623-8 |
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