Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant

The single-nucleotide polymorphism (SNP) of p53, in particular the codon 72 variants, has recently been implicated as a critical regulator in tumor progression. However, the underlying mechanism remains elusive. Here we found that cancer cells carrying codon 72-Pro variant of p53 showed impaired met...

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Detalles Bibliográficos
Autores principales: Jiang, Jingwen, Chen, Hai-Ning, Jin, Ping, Zhou, Li, Peng, Liyuan, Huang, Zhao, Qin, Siyuan, Li, Bowen, Ming, Hui, Luo, Maochao, Xie, Na, Gao, Wei, Nice, Edouard C., Yu, Qiang, Huang, Canhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929071/
https://www.ncbi.nlm.nih.gov/pubmed/36788227
http://dx.doi.org/10.1038/s41392-022-01266-7

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