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Single-cell sequencing of ascites fluid illustrates heterogeneity and therapy-induced evolution during gastric cancer peritoneal metastasis

Peritoneal metastasis is the leading cause of death for gastrointestinal cancers. The native and therapy-induced ascites ecosystems are not fully understood. Here, we characterize single-cell transcriptomes of 191,987 ascites cancer/immune cells from 35 patients with/without gastric cancer peritonea...

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Detalles Bibliográficos
Autores principales: Huang, Xuan-Zhang, Pang, Min-Jiao, Li, Jia-Yi, Chen, Han-Yu, Sun, Jing-Xu, Song, Yong-Xi, Ni, Hong-Jie, Ye, Shi-Yu, Bai, Shi, Li, Teng-Hui, Wang, Xin-Yu, Lu, Jing-Yuan, Yang, Jin-Jia, Sun, Xun, Mills, Jason C., Miao, Zhi-Feng, Wang, Zhen-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929081/
https://www.ncbi.nlm.nih.gov/pubmed/36788228
http://dx.doi.org/10.1038/s41467-023-36310-9