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Hybrid autoencoder with orthogonal latent space for robust population structure inference

Analysis of population structure and genomic ancestry remains an important topic in human genetics and bioinformatics. Commonly used methods require high-quality genotype data to ensure accurate inference. However, in practice, laboratory artifacts and outliers are often present in the data. Moreove...

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Detalles Bibliográficos
Autores principales: Yuan, Meng, Hoskens, Hanne, Goovaerts, Seppe, Herrick, Noah, Shriver, Mark D., Walsh, Susan, Claes, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929087/
https://www.ncbi.nlm.nih.gov/pubmed/36788253
http://dx.doi.org/10.1038/s41598-023-28759-x