Profiling the peripheral immune response to ex vivo TNF stimulation in untreated juvenile idiopathic arthritis using single cell RNA sequencing

BACKGROUND: Juvenile Idiopathic Arthritis (JIA) is an autoimmune disease with a heterogenous clinical presentation and unpredictable response to available therapies. This personalized transcriptomics study sought proof-of-concept for single-cell RNA sequencing to characterize patient-specific immune...

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Detalles Bibliográficos
Autores principales: Imbach, Kathleen J., Treadway, Nicole J., Prahalad, Vaishali, Kosters, Astrid, Arafat, Dalia, Duan, Meixue, Gergely, Talia, Ponder, Lori A., Chandrakasan, Shanmuganathan, Ghosn, Eliver E. B., Prahalad, Sampath, Gibson, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929251/
https://www.ncbi.nlm.nih.gov/pubmed/36793127
http://dx.doi.org/10.1186/s12969-023-00787-x

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