Role of Dipolar Interactions on the Determination of the Effective Magnetic Anisotropy in Iron Oxide Nanoparticles

Challenging magnetic hyperthermia (MH) applications of immobilized magnetic nanoparticles require detailed knowledge of the effective anisotropy constant (K (eff)) to maximize heat release. Designing optimal MH experiments entails the precise determination of magnetic properties, which are, however, affected by the unavoidable concurrence of magnetic interactions in common experimental conditions. In this work, a mean‐field energy barrier model (ΔE), accounting for anisotropy (E(A) ) and magnetic dipolar (E(D) ) energy, is proposed and used in combination with AC measurements to a specifically developed model system of spherical magnetic nanoparticles with well‐controlled silica shells, acting as a spacer between the magnetic cores. This approach makes it possible to experimentally demonstrate the mean field dipolar interaction energy prediction with the interparticle distance, d(ij), E(D) ≈ 1/d(ij) (3) and obtain the E (A) as the asymptotic limit for very large d(ij). In doing so, K (eff) uncoupled from interaction contributions is obtained for the model system (iron oxide cores with average sizes of 8.1, 10.2, and 15.3 nm) revealing to be 48, 23, and 11 kJ m(−3), respectively, close to bulk magnetite/maghemite values and independent from the specific spacing shell thicknesses selected for the study.