RNF126‐Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple‐Negative Breast Cancer to Radiotherapy

Triple‐negative breast cancer (TNBC) has higher molecular heterogeneity and metastatic potential and the poorest prognosis. Because of limited therapeutics against TNBC, irradiation (IR) therapy is still a common treatment option for patients with lymph nodes or brain metastasis. Thus, it is urgent...

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Detalles Bibliográficos
Autores principales: Liu, Wenjing, Zheng, Min, Zhang, Rou, Jiang, Qiuyun, Du, Guangshi, Wu, Yingying, Yang, Chuanyu, Li, Fubing, Li, Wei, Wang, Luzhen, Wu, Jiao, Shi, Lei, Li, Wenhui, Zhang, Kai, Zhou, Zhongmei, Liu, Rong, Gao, Yingzheng, Huang, Xinwei, Fan, Songqing, Zhi, Xu, Jiang, Dewei, Chen, Ceshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929257/
https://www.ncbi.nlm.nih.gov/pubmed/36563124
http://dx.doi.org/10.1002/advs.202203884

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