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Ensembles of human myosin-19 bound to calmodulin and regulatory light chain RLC12B drive multimicron transport

Myosin-19 (Myo19) controls the size, morphology, and distribution of mitochondria, but the underlying role of Myo19 motor activity is unknown. Complicating mechanistic in vitro studies, the identity of the light chains (LCs) of Myo19 remains unsettled. Here, we show by coimmunoprecipitation, reconst...

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Detalles Bibliográficos
Autores principales:	Pollard, Luther W., Coscia, Stephen M., Rebowski, Grzegorz, Palmer, Nicholas J., Holzbaur, Erika L.F., Dominguez, Roberto, Ostap, E. Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929473/ https://www.ncbi.nlm.nih.gov/pubmed/36642185 http://dx.doi.org/10.1016/j.jbc.2023.102906

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