Hydropersulfides (RSSH) attenuate doxorubicin-induced cardiotoxicity while boosting its anticancer action

Cardiotoxicity is a frequent and often lethal complication of doxorubicin (DOX)-based chemotherapy. Here, we report that hydropersulfides (RSSH) are the most effective reactive sulfur species in conferring protection against DOX-induced toxicity in H9c2 cardiac cells. Mechanistically, RSSH supplemen...

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Detalles Bibliográficos
Autores principales: Pharoah, Blaze M., Zhang, Chengximeng, Khodade, Vinayak S., Keceli, Gizem, McGinity, Christopher, Paolocci, Nazareno, Toscano, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles from the Special Issue on Recent advances in sulfur biology and chemistry, Edited by: Dr. Peter Nagy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929489/
https://www.ncbi.nlm.nih.gov/pubmed/36773545
http://dx.doi.org/10.1016/j.redox.2023.102625

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