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Knockdown of hepatocyte Perilipin-3 mitigates hepatic steatosis and steatohepatitis caused by hepatocyte CGI-58 deletion in mice

Comparative gene identification-58 (CGI-58), also known as α/β hydrolase domain containing 5, is the co-activator of adipose triglyceride lipase that hydrolyzes triglycerides stored in the cytosolic lipid droplets. Mutations in CGI-58 gene cause Chanarin–Dorfman syndrome (CDS), an autosomal recessiv...

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Detalles Bibliográficos
Autores principales: Bao, Xinyu, Ma, Xiaogen, Huang, Rongfeng, Chen, Jianghui, Xin, Haoran, Zhou, Meiyu, Li, Lihua, Tong, Shifei, Zhang, Qian, Shui, Guanghou, Deng, Fang, Yu, Liqing, Li, Min-Dian, Zhang, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929509/
https://www.ncbi.nlm.nih.gov/pubmed/36107452
http://dx.doi.org/10.1093/jmcb/mjac055