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Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer

Chimeric antigen receptor (CAR) T-cell therapy can lead to dramatic clinical responses in B-cell malignancies. However, early clinical trials with CAR T-cell therapy in non–B-cell malignancies have been disappointing to date, suggesting that tumor-intrinsic features contribute to resistance. To inve...

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Detalles Bibliográficos
Autores principales:	Hagel, Kimberly R., Arafeh, Rand, Gang, Sydney, Arnoff, Taylor E., Larson, Rebecca C., Doench, John G., Mathewson, Nathan D., Wucherpfennig, Kai W., Maus, Marcela V., Hahn, William C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Tumor Biology and Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929516/ https://www.ncbi.nlm.nih.gov/pubmed/36548402 http://dx.doi.org/10.1158/0008-5472.CAN-22-2245

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