Mast cell activation mediates blood–brain barrier impairment and cognitive dysfunction in septic mice in a histamine-dependent pathway

INTRODUCTION: Sepsis-associated encephalopathy (SAE) is a diffuse cerebral dysfunction resulting from a systemic inflammatory response to infection; however, its pathophysiology remains unclear. Sepsis-induced neuroinflammation and blood–brain barrier (BBB) disruption are crucial factors in brain fu...

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Detalles Bibliográficos
Autores principales: Yue, Jianhe, Tan, Ying, Huan, Renzheng, Guo, Jin, Yang, Sha, Deng, Mei, Xiong, Yunbiao, Han, Guoqiang, Liu, Lin, Liu, Jian, Cheng, Yuan, Zha, Yan, Zhang, Jiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929573/
https://www.ncbi.nlm.nih.gov/pubmed/36817492
http://dx.doi.org/10.3389/fimmu.2023.1090288

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