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Role of human HSPE1 for OPA1 processing independent of HSPD1

The human mtHSP60/HSPD1-mtHSP10/HSPE1 system prevents protein misfolding and maintains proteostasis in the mitochondrial matrix. Altered activities of this chaperonin system have been implicated in human diseases, such as cancer and neurodegeneration. However, how defects in HSPD1 and HSPE1 affect m...

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Detalles Bibliográficos
Autores principales: Yeung, Nelson, Murata, Daisuke, Iijima, Miho, Sesaki, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929679/
https://www.ncbi.nlm.nih.gov/pubmed/36818283
http://dx.doi.org/10.1016/j.isci.2023.106067