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Etiology and clinical characteristics of primary epistaxis
BACKGROUND: Primary epistaxis (rupture of nasal artery vessels) is a common emergency, but the related factors are still controversial. This study collected the data on primary epistaxis patients and healthy people undergoing a physical examination at the same center to explore and classify primary...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929811/ https://www.ncbi.nlm.nih.gov/pubmed/36819513 http://dx.doi.org/10.21037/atm-22-6590 |
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author | Li, Hai-Yan Luo, Ting Li, Liang Liu, Ying Zhai, Xiang Wang, Xu-Dong |
author_facet | Li, Hai-Yan Luo, Ting Li, Liang Liu, Ying Zhai, Xiang Wang, Xu-Dong |
author_sort | Li, Hai-Yan |
collection | PubMed |
description | BACKGROUND: Primary epistaxis (rupture of nasal artery vessels) is a common emergency, but the related factors are still controversial. This study collected the data on primary epistaxis patients and healthy people undergoing a physical examination at the same center to explore and classify primary epistaxis by its characteristics. METHODS: Primary epistaxis was divided into septal epistaxis and non-septal epistaxis, and logistic regression was performed to determine the risk factors. RESULTS: In total, 196 cases of septal epistaxis and 127 cases of non-septal epistaxis, and the control group was 182 healthy subjects. There were significant differences in sex, drinking history, hypertension history and hyperlipidemia between the bleeding group and the control group, but no correlation with smoking, diabetes, cardiovascular and cerebrovascular events, or anticoagulant drug use. In the age group of 26–40 years it was related to alcohol consumption and hypertension, for those aged 41–55 years it was related to hypertension, in the age group of 56–70 years it was related to hypertension, high triglyceride and high apolipoprotein B levels, and no related factors were found in the age group >70 years. The risk factors for non-septal cases were increased low-density lipoprotein (LDL) [P=0.035; odds ratio (OR), 2.450; 95% confidence interval (CI): 1.067–5.624], male sex (P=0.002; OR, 3.136; 95% CI: 1.501–6.554), and younger age (P=0.000; OR, 0.941; 95%CI: 0.920–0.962). All patients with nosebleed underwent nasal endoscopy and the bleeding site was successfully located and treated with electrocoagulation. No further bleeding or serious complications occurred after 6 months of follow-up. CONCLUSIONS: Primary epistaxis is more common in males and is related to alcohol consumption, hypertension, and hyperlipidemia. In the young age groups, male sex, and increased LDL were high risk factors for non-septal hemorrhage in winter and spring. Nasal endoscopy and electrocoagulation are safe and effective. |
format | Online Article Text |
id | pubmed-9929811 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-99298112023-02-16 Etiology and clinical characteristics of primary epistaxis Li, Hai-Yan Luo, Ting Li, Liang Liu, Ying Zhai, Xiang Wang, Xu-Dong Ann Transl Med Original Article BACKGROUND: Primary epistaxis (rupture of nasal artery vessels) is a common emergency, but the related factors are still controversial. This study collected the data on primary epistaxis patients and healthy people undergoing a physical examination at the same center to explore and classify primary epistaxis by its characteristics. METHODS: Primary epistaxis was divided into septal epistaxis and non-septal epistaxis, and logistic regression was performed to determine the risk factors. RESULTS: In total, 196 cases of septal epistaxis and 127 cases of non-septal epistaxis, and the control group was 182 healthy subjects. There were significant differences in sex, drinking history, hypertension history and hyperlipidemia between the bleeding group and the control group, but no correlation with smoking, diabetes, cardiovascular and cerebrovascular events, or anticoagulant drug use. In the age group of 26–40 years it was related to alcohol consumption and hypertension, for those aged 41–55 years it was related to hypertension, in the age group of 56–70 years it was related to hypertension, high triglyceride and high apolipoprotein B levels, and no related factors were found in the age group >70 years. The risk factors for non-septal cases were increased low-density lipoprotein (LDL) [P=0.035; odds ratio (OR), 2.450; 95% confidence interval (CI): 1.067–5.624], male sex (P=0.002; OR, 3.136; 95% CI: 1.501–6.554), and younger age (P=0.000; OR, 0.941; 95%CI: 0.920–0.962). All patients with nosebleed underwent nasal endoscopy and the bleeding site was successfully located and treated with electrocoagulation. No further bleeding or serious complications occurred after 6 months of follow-up. CONCLUSIONS: Primary epistaxis is more common in males and is related to alcohol consumption, hypertension, and hyperlipidemia. In the young age groups, male sex, and increased LDL were high risk factors for non-septal hemorrhage in winter and spring. Nasal endoscopy and electrocoagulation are safe and effective. AME Publishing Company 2023-01-31 2023-01-31 /pmc/articles/PMC9929811/ /pubmed/36819513 http://dx.doi.org/10.21037/atm-22-6590 Text en 2023 Annals of Translational Medicine. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Original Article Li, Hai-Yan Luo, Ting Li, Liang Liu, Ying Zhai, Xiang Wang, Xu-Dong Etiology and clinical characteristics of primary epistaxis |
title | Etiology and clinical characteristics of primary epistaxis |
title_full | Etiology and clinical characteristics of primary epistaxis |
title_fullStr | Etiology and clinical characteristics of primary epistaxis |
title_full_unstemmed | Etiology and clinical characteristics of primary epistaxis |
title_short | Etiology and clinical characteristics of primary epistaxis |
title_sort | etiology and clinical characteristics of primary epistaxis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929811/ https://www.ncbi.nlm.nih.gov/pubmed/36819513 http://dx.doi.org/10.21037/atm-22-6590 |
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