Impact of carbapenem antibiotics on mycophenolate mofetil in hematopoietic stem cell transplant patients with interruption of the enterohepatic recycling: a retrospective study

BACKGROUND: Mycophenolate mofetil (MMF), a prodrug of mycophenolic acid (MPA), is widely used in the prophylaxis for graft-versus-host disease (GVHD) following hematopoietic stem cell transplantation (HSCT). MPA undergoes enterohepatic recycling (EHR). Oral antibiotics can affect MPA concentration b...

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Detalles Bibliográficos
Autores principales: Tian, Ji-Xin, Miao, Wen-Juan, Yan, Hai-Hong, Wang, Xiao-Dan, Liao, Ying-Xi, Li, Shan, Jiang, Er-Lie, Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929831/
https://www.ncbi.nlm.nih.gov/pubmed/36819591
http://dx.doi.org/10.21037/atm-22-6341

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