Cargando…

The efficacy of thoracic radiotherapy in extensive stage small cell lung cancer with baseline brain metastases: a multi-institutional retrospective cohort study

BACKGROUND: Thoracic radiotherapy (TRT) had been shown to improve overall survival (OS) in extensive-stage small cell lung cancer (ES-SCLC) patients. However, approximately one fourth of SCLC harbored baseline brain metastases (BMs) and were excluded from previous TRT trials. Thus, the role of TRT i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Zhiqin, Yuan, Xun, Zhou, Yue, Chu, Li, Yang, Xi, Ni, Jianjiao, Chu, Qian, Chu, Xiao, Liu, Yanfei, Zhu, Zhengfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929839/ https://www.ncbi.nlm.nih.gov/pubmed/36819545 http://dx.doi.org/10.21037/atm-22-5853

Ejemplares similares

A nomogram to predict the overall survival of patients with symptomatic extensive-stage small cell lung cancer treated with thoracic radiotherapy
por: Yuan, Xun, et al.
Publicado: (2021)

Optimal timing and clinical value of radiotherapy in advanced ALK-rearranged non-small cell lung cancer with or without baseline brain metastases: implications from pattern of failure analyses
por: Ni, Jianjiao, et al.
Publicado: (2019)

Recommendation for the definition of postoperative radiotherapy target volume based on a pooled analysis of patterns of failure after radical surgery among patients with thoracic esophageal squamous cell carcinoma
por: Zhang, Xiaofei, et al.
Publicado: (2018)

Rationale and value of consolidative cranial local therapy in EGFR-mutant non-small cell lung cancer patients with baseline brain metastasis treated with first-line EGFR-TKIs
por: Zeng, Ya, et al.
Publicado: (2023)

Low‐ dose Apatinib promotes vascular normalization and hypoxia reduction and sensitizes radiotherapy in lung cancer
por: Jiang, Shanshan, et al.
Publicado: (2022)

Brain metastases, patterns of intracranial progression, and the clinical value of upfront cranial radiotherapy in patients with metastatic non-small cell lung cancer treated with PD-1/PD-L1 inhibitors
por: Guo, Tiantian, et al.
Publicado: (2022)

Radiotherapy for unresectable locally advanced non-small cell lung cancer: a narrative review of the current landscape and future prospects in the era of immunotherapy
por: Guo, Tiantian, et al.
Publicado: (2020)

Outcomes for Surgery in Stage IA Large Cell Lung Neuroendocrine Compared With Other Types of Non-Small Cell Lung Cancer: A Propensity Score Matching Study Based on the Surveillance, Epidemiology, and End Results (SEER) Database
por: Zou, Liqing, et al.
Publicado: (2020)

A narrative review of evolving roles of radiotherapy in advanced non-small cell lung cancer: from palliative care to active player
por: Zhou, Yue, et al.
Publicado: (2020)

Is clinical target volume necessary?—a failure pattern analysis in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy using intensity-modulated radiotherapy technique
por: Zou, Liqing, et al.
Publicado: (2020)

Clinical outcomes of advanced non-small cell lung cancer patients harboring distinct subtypes of EGFR mutations and receiving first-line tyrosine kinase inhibitors: brain metastasis and de novo T790M matters
por: Zeng, Ya, et al.
Publicado: (2022)

A “Seed-and-Soil” Radiomics Model Predicts Brain Metastasis Development in Lung Cancer: Implications for Risk-Stratified Prophylactic Cranial Irradiation
por: Chu, Xiao, et al.
Publicado: (2023)

Patterns of brain metastasis immediately before prophylactic cranial irradiation (PCI): implications for PCI optimization in limited-stage small cell lung cancer
por: Chu, Xiao, et al.
Publicado: (2019)

Identification of lncRNA, MicroRNA, and mRNA-Associated CeRNA Network of Radiation-Induced Lung Injury in a Mice Model
por: Li, Yida, et al.
Publicado: (2019)

Sintilimab, stereotactic body radiotherapy and granulocyte–macrophage colony stimulating factor as second-line therapy for advanced non-small cell lung cancer: safety run-in results of a multicenter, single-arm, phase II trial
por: Ni, Jianjiao, et al.
Publicado: (2021)

A narrative review of synergistic drug administration in unresectable locally advanced non-small cell lung cancer: current landscape and future prospects in the era of immunotherapy
por: Li, Shuyan, et al.
Publicado: (2020)

Identification and Integrated Analysis of circRNA and miRNA of Radiation-Induced Lung Injury in a Mouse Model
por: Li, Yida, et al.
Publicado: (2021)

Pattern of failure and clinical value of local therapy for oligo‐recurrence in locally advanced non‐small cell lung cancer after definitive chemoradiation: Impact of driver mutation status
por: Zhang, Jinmeng, et al.
Publicado: (2022)

LncRNA-RP11 Modulates TGF-β1-Activated Radiation-Induced Lung Injury Through Downregulating microRNA-29a
por: Yang, Xi, et al.
Publicado: (2020)

Consolidative thoracic radiotherapy for extensive stage small cell lung cancer
por: Zhang, Xiaoli, et al.
Publicado: (2017)

The value of local consolidative therapy in Osimertinib-treated non-small cell lung cancer with oligo-residual disease
por: Zeng, Ya, et al.
Publicado: (2020)

Atypical Response in Metastatic Non-Small Cell Lung Cancer Treated with PD-1/PD-L1 Inhibitors: Radiographic Patterns and Clinical Value of Local Therapy
por: Jiang, Shanshan, et al.
Publicado: (2022)

Liquid‐based cell suspension of supraclavicular lymph node fine‐needle aspirate as an alternative specimen for NGS‐based genomic profiling in advanced lung cancer
por: Zhang, Xun, et al.
Publicado: (2020)

Is Performance of Fluorine-18-fluorodeoxyglucose Positron Emission Tomography/Computed tomography (CT) or Contrast-enhanced CT Efficient Enough to Guide the Hilar Lymph Node Staging for Patients with Esophageal Squamous Cell Carcinoma?
por: Chu, Li, et al.
Publicado: (2022)

Supraclavicular Recurrence in Completely Resected (y)pN2 Non-Small Cell Lung Cancer: Implications for Postoperative Radiotherapy
por: Liu, Liang, et al.
Publicado: (2020)

Pneumonitis in Patients Receiving Thoracic Radiotherapy and Osimertinib: A Multi-Institutional Study
por: Banla, Leou Ismael, et al.
Publicado: (2023)

Role of thoracic radiotherapy in extensive stage small cell lung cancer: a systemic review and meta-analysis
por: Li, Ao-Mei, et al.
Publicado: (2021)

Risk factors of postoperative recurrence and potential candidate of adjuvant radiotherapy in lung adenosquamous carcinoma
por: Ni, Jianjiao, et al.
Publicado: (2020)

Timing of thoracic radiotherapy in the treatment of extensive-stage small-cell lung cancer: important or not?
por: Luo, Jing, et al.
Publicado: (2017)

The role of thoracic consolidative radiotherapy in the setting of immunotherapy in extensive stage small cell lung cancer
por: Verma, Saurav, et al.
Publicado: (2023)

Regulatory T Cells: An Emerging Player in Radiation-Induced Lung Injury
por: Guo, Tiantian, et al.
Publicado: (2020)

Thoracic Radiotherapy Benefits Elderly Extensive-Stage Small Cell Lung Cancer Patients with Distant Metastasis
por: Qi, Jing, et al.
Publicado: (2019)

Para-aortic lymph node metastasis in lower Thoracic Esophageal Squamous Cell Carcinoma after Radical Esophagectomy: a CT-based atlas and its clinical implications for Adjuvant Radiotherapy
por: Ye, Luxi, et al.
Publicado: (2021)

Thoracic radiotherapy (TRT) improved survival in both oligo- and polymetastatic extensive stage small cell lung cancer
por: Xu, Li-Ming, et al.
Publicado: (2017)

What is the role of consolidative thoracic radiotherapy in the era of chemo-immunotherapy for extensive stage small cell lung cancer?
por: Higgins, Kristin A., et al.
Publicado: (2020)

STING signaling activation modulates macrophage polarization via CCL2 in radiation-induced lung injury
por: Ni, Jianjiao, et al.
Publicado: (2023)

Consolidative Thoracic Radiation Therapy After First-Line Chemotherapy and Immunotherapy in Extensive-Stage Small Cell Lung Cancer: A Multi-Institutional Case Series
por: Diamond, Brett H., et al.
Publicado: (2021)

Radiographic Features of Metastatic Brain Tumors from ALK-rearranged Non-small Cell Lung Cancer: Implications for Optimal Treatment Modalities
por: Chu, Li, et al.
Publicado: (2019)

Safety and efficacy of stereotactic body radiotherapy as primary treatment for vertebral metastases: a multi-institutional analysis
por: Guckenberger, Matthias, et al.
Publicado: (2014)

Clinical outcomes of extensive-stage small cell lung cancer patients treated with thoracic radiotherapy at different times and fractionations
por: Han, Jinmin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_563vn26s5k3svbaf2cck9tddsc