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A loosely coordinated interaction site for arachidonic acid on ASICs

Molecular dynamics simulations reveal a putative interaction surface for PUFAs on TM1 of ASICs that is not tightly conserved between isoforms.

Detalles Bibliográficos
Autores principales: Klipp, Robert C., Bankston, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9929933/
https://www.ncbi.nlm.nih.gov/pubmed/36723670
http://dx.doi.org/10.1085/jgp.202213307
Descripción
Sumario:Molecular dynamics simulations reveal a putative interaction surface for PUFAs on TM1 of ASICs that is not tightly conserved between isoforms.