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Adenopathies: A Confusing Presentation of Primary Biliary Cholangitis
Primary biliary cholangitis (PBC) is an autoimmune disease in which the intrahepatic bile ducts are destroyed. Its symptoms include chronic fatigue, pruritus, steatorrhea, and jaundice, with variable clinical course. We are introducing a case of a 65-year-old woman with anorexia, weight loss, asthen...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930001/ https://www.ncbi.nlm.nih.gov/pubmed/36819325 http://dx.doi.org/10.7759/cureus.33814 |
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author | Maciel, Catarina Augusto, Daniela Tenreiro, Nadia Martins, Filipe |
author_facet | Maciel, Catarina Augusto, Daniela Tenreiro, Nadia Martins, Filipe |
author_sort | Maciel, Catarina |
collection | PubMed |
description | Primary biliary cholangitis (PBC) is an autoimmune disease in which the intrahepatic bile ducts are destroyed. Its symptoms include chronic fatigue, pruritus, steatorrhea, and jaundice, with variable clinical course. We are introducing a case of a 65-year-old woman with anorexia, weight loss, asthenia, and pruritus. The imaging studies revealed dilatation of the intrahepatic and common bile ducts and adenopathies at the level of the hepatoduodenal ligament, histologically compatible with reactive lymphadenitis. After the exclusion of neoplasia, she was referred to Internal Medicine where positivity was obtained for anti-mitochondrial autoantibodies suggestive of PBC. After the initiation of therapy, there was a resolution of the clinical symptoms and the adenopathies were no longer detected in subsequent studies. The authors intend to highlight this case, especially due to the presence of adenopathies and constitutional symptoms where PBC should also be considered, as a differential diagnosis. |
format | Online Article Text |
id | pubmed-9930001 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-99300012023-02-16 Adenopathies: A Confusing Presentation of Primary Biliary Cholangitis Maciel, Catarina Augusto, Daniela Tenreiro, Nadia Martins, Filipe Cureus Internal Medicine Primary biliary cholangitis (PBC) is an autoimmune disease in which the intrahepatic bile ducts are destroyed. Its symptoms include chronic fatigue, pruritus, steatorrhea, and jaundice, with variable clinical course. We are introducing a case of a 65-year-old woman with anorexia, weight loss, asthenia, and pruritus. The imaging studies revealed dilatation of the intrahepatic and common bile ducts and adenopathies at the level of the hepatoduodenal ligament, histologically compatible with reactive lymphadenitis. After the exclusion of neoplasia, she was referred to Internal Medicine where positivity was obtained for anti-mitochondrial autoantibodies suggestive of PBC. After the initiation of therapy, there was a resolution of the clinical symptoms and the adenopathies were no longer detected in subsequent studies. The authors intend to highlight this case, especially due to the presence of adenopathies and constitutional symptoms where PBC should also be considered, as a differential diagnosis. Cureus 2023-01-16 /pmc/articles/PMC9930001/ /pubmed/36819325 http://dx.doi.org/10.7759/cureus.33814 Text en Copyright © 2023, Maciel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Maciel, Catarina Augusto, Daniela Tenreiro, Nadia Martins, Filipe Adenopathies: A Confusing Presentation of Primary Biliary Cholangitis |
title | Adenopathies: A Confusing Presentation of Primary Biliary Cholangitis |
title_full | Adenopathies: A Confusing Presentation of Primary Biliary Cholangitis |
title_fullStr | Adenopathies: A Confusing Presentation of Primary Biliary Cholangitis |
title_full_unstemmed | Adenopathies: A Confusing Presentation of Primary Biliary Cholangitis |
title_short | Adenopathies: A Confusing Presentation of Primary Biliary Cholangitis |
title_sort | adenopathies: a confusing presentation of primary biliary cholangitis |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930001/ https://www.ncbi.nlm.nih.gov/pubmed/36819325 http://dx.doi.org/10.7759/cureus.33814 |
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