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Is PEGylation of Drugs Associated with Hypersensitivity Reactions? An Analysis of the Italian National Spontaneous Adverse Drug Reaction Reporting System
BACKGROUND AND OBJECTIVE: Evidence highlights the allergenic potential of PEGylated drugs because of the production of anti-polyethylene glycol immunoglobulins. We investigated the risk of hypersensitivity reactions of PEGylated drugs using the Italian spontaneous adverse drug reaction reporting sys...
Autores principales: | Crisafulli, Salvatore, Cutroneo, Paola Maria, Luxi, Nicoletta, Fontana, Andrea, Ferrajolo, Carmen, Marchione, Pasquale, Sottosanti, Laura, Zanoni, Giovanna, Moretti, Ugo, Franzè, Silvia, Minghetti, Paola, Trifirò, Gianluca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930046/ https://www.ncbi.nlm.nih.gov/pubmed/36790561 http://dx.doi.org/10.1007/s40264-023-01277-5 |
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