RLC phosphorylation amplifies Ca(2+) sensitivity of force in myocardium from cMyBP-C knockout mice

Hypertrophic cardiomyopathy (HCM) is the leading genetic cause of heart disease. The heart comprises several proteins that work together to properly facilitate force production and pump blood throughout the body. Cardiac myosin binding protein-C (cMyBP-C) is a thick-filament protein, and mutations i...

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Detalles Bibliográficos
Autores principales: Turner, Kyrah L., Morris, Haley S., Awinda, Peter O., Fitzsimons, Daniel P., Tanner, Bertrand C.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930131/
https://www.ncbi.nlm.nih.gov/pubmed/36715675
http://dx.doi.org/10.1085/jgp.202213250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930131/
https://www.ncbi.nlm.nih.gov/pubmed/36715675
http://dx.doi.org/10.1085/jgp.202213250

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