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Tubulin isotype regulation maintains asymmetric requirement for α-tubulin over β-tubulin

How cells regulate α- and β-tubulin to meet the demand for αβ-heterodimers and avoid consequences of monomer imbalance is not understood. We investigate the role of gene copy number and how shifting expression of α- or β-tubulin genes impacts tubulin proteostasis and microtubule function in Saccharo...

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Detalles Bibliográficos
Autores principales:	Wethekam, Linnea C., Moore, Jeffrey K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930134/ https://www.ncbi.nlm.nih.gov/pubmed/36719400 http://dx.doi.org/10.1083/jcb.202202102

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