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Tex2 is required for lysosomal functions at TMEM55-dependent ER membrane contact sites

ER tubules form and maintain membrane contact sites (MCSs) with late endosomes/lysosomes (LE/lys). The molecular composition and cellular functions of these MCSs are poorly understood. Here, we find that Tex2, an SMP domain-containing lipid transfer protein conserved in metazoan and yeast, is a tubu...

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Detalles Bibliográficos
Autores principales:	Du, Yuanjiao, Chang, Weiping, Gao, Lei, Deng, Lin, Ji, Wei-Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930140/ https://www.ncbi.nlm.nih.gov/pubmed/36705603 http://dx.doi.org/10.1083/jcb.202205133

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