Rapid molecular imaging of active thrombi in vivo using aptamer-antidote probes

Pathological blood clotting, or thrombosis, limits vital blood flow to organs; such deprivation can lead to catastrophic events including myocardial infarction, pulmonary embolism, and ischemic stroke. Prompt restoration of blood flow greatly improves outcomes. We explored whether aptamers could ser...

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Detalles Bibliográficos
Autores principales: Gray, Bethany Powell, Kelly, Linsley, Steen-Burrell, Kady-Ann, Layzer, Juliana M., Rempel, Rachel E., Nimjee, Shahid M., Cooley, Brian C., Tarantal, Alice F., Sullenger, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930157/
https://www.ncbi.nlm.nih.gov/pubmed/36817726
http://dx.doi.org/10.1016/j.omtn.2023.01.009

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