Exosomal circTUBGCP4 promotes vascular endothelial cell tipping and colorectal cancer metastasis by activating Akt signaling pathway

BACKGROUND: Exosome is crucial mediator and play an important role in tumor angiogenesis. Tip cell formation is a prerequisite for persistent tumor angiogenesis which causes tumor metastasis. However, the functions and underlying mechanisms of tumor cell-derived exosomes in angiogenesis and tip cell...

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Detalles Bibliográficos
Autores principales: Chen, Chen, Liu, Yang, Liu, Lin, Si, Chaohua, Xu, Yanxin, Wu, Xiaoke, Wang, Chengzeng, Sun, Zhenqiang, Kang, Qiaozhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930311/
https://www.ncbi.nlm.nih.gov/pubmed/36793126
http://dx.doi.org/10.1186/s13046-023-02619-y

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