Cargando…

Wogonin attenuates the pathogenicity of Streptococcus pneumoniae by double‐target inhibition of Pneumolysin and Sortase A

Streptococcus pneumoniae (S. pneumoniae) is a major causative agent of respiratory disease in patients and can cause respiratory distress and other symptoms in severe cases. Pneumolysin (PLY) is a pore‐forming toxin that induces host tissue injury and inflammatory responses. Sortase A (SrtA), a cata...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Kuan, Ding, Lizhong, Wang, Zhongtian, Sun, Yingying, Sun, Xiaozhou, Yang, Wenbo, Sun, Haihang, Tian, Ye, Wang, Zeyu, Sun, Liping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930429/ https://www.ncbi.nlm.nih.gov/pubmed/36747468 http://dx.doi.org/10.1111/jcmm.17684

Ejemplares similares

Cortex Cercis chinensis Granules Attenuate Streptococcus pneumoniae Virulence by Targeting Pneumolysin
por: Xu, Yan, et al.
Publicado: (2020)

Epigallocatechin gallate inhibits Streptococcus pneumoniae virulence by simultaneously targeting pneumolysin and sortase A
por: Song, Meng, et al.
Publicado: (2017)

Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release
por: Bryant, Joseph C., et al.
Publicado: (2016)

β-sitosterol interacts with pneumolysin to prevent Streptococcus pneumoniae infection
por: Li, Hongen, et al.
Publicado: (2015)

The Impact of Pneumolysin on the Macrophage Response to Streptococcus pneumoniae is Strain-Dependent
por: Harvey, Richard M., et al.
Publicado: (2014)

Novel Role for the Streptococcus pneumoniae Toxin Pneumolysin in the Assembly of Biofilms
por: Shak, Joshua R., et al.
Publicado: (2013)

Gut Microbiota and SCFAs Play Key Roles in QingFei Yin Recipe Anti-Streptococcal Pneumonia Effects
por: Sun, Xiaozhou, et al.
Publicado: (2021)

Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression
por: Littmann, Marie, et al.
Publicado: (2009)

Pneumolysin boosts the neuroinflammatory response to Streptococcus pneumoniae through enhanced endocytosis
por: Hupp, Sabrina, et al.
Publicado: (2022)

Pneumolysin suppresses the initial macrophage pro‐inflammatory response to Streptococcus pneumoniae
por: Periselneris, Jimstan, et al.
Publicado: (2022)

Quercetin impairs Streptococcus pneumoniae biofilm formation by inhibiting sortase A activity
por: Wang, Jianfeng, et al.
Publicado: (2018)

Pneumolysin and the bacterial capsule of Streptococcus pneumoniae cooperatively inhibit taxis and motility of microglia
por: Hupp, Sabrina, et al.
Publicado: (2019)

Targeted control of pneumolysin production by a mobile genetic element in Streptococcus pneumoniae
por: Stevens, Emily J., et al.
Publicado: (2022)

Activation of Autophagy Through the NLRP3/mTOR Pathway: A Potential Mechanism for Alleviation of Pneumonia by QingFei Yin
por: Sun, Xiaozhou, et al.
Publicado: (2022)

In silico identification of potential inhibitors targeting Streptococcus mutans sortase A
por: Luo, Hao, et al.
Publicado: (2017)

Corilagin: A Novel Antivirulence Strategy to Alleviate Streptococcus pneumoniae Infection by Diminishing Pneumolysin Oligomers
por: Sheng, Qiushuang, et al.
Publicado: (2022)

Peptidoglycan Branched Stem Peptides Contribute to Streptococcus pneumoniae Virulence by Inhibiting Pneumolysin Release
por: Greene, Neil G., et al.
Publicado: (2015)

Fatal infection in adults by pneumolysin & autolysin producing, non-vaccine serotype Streptococcus pneumonia
por: Kanungo, Reba, et al.
Publicado: (2016)

Shionone-Targeted Pneumolysin to Ameliorate Acute Lung Injury Induced by Streptococcus pneumoniae In Vivo and In Vitro
por: Du, Runbao, et al.
Publicado: (2022)

Molecular Mechanisms of the Binding and Specificity of Streptococcus Pneumoniae Sortase C Enzymes for Pilin Subunits
por: Naziga, Emmanuel B., et al.
Publicado: (2017)

Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation
por: Lawrence, Sara L., et al.
Publicado: (2015)

Heterogeneity in pneumolysin expression governs the fate of Streptococcus pneumoniae during blood-brain barrier trafficking
por: Surve, Manalee Vishnu, et al.
Publicado: (2018)

Matcha Green Tea Exhibits Bactericidal Activity against Streptococcus pneumoniae and Inhibits Functional Pneumolysin
por: Sasagawa, Karin, et al.
Publicado: (2021)

Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles
por: Syed, Shahan, et al.
Publicado: (2021)

Astilbin Inhibits the Activity of Sortase A from Streptococcus mutans
por: Wang, Junxian, et al.
Publicado: (2019)

Role of sortase in Streptococcus mutans under the effect of nicotine
por: Li, Ming-Yun, et al.
Publicado: (2013)

Extracellular Calcium Reduction Strongly Increases the Lytic Capacity of Pneumolysin From Streptococcus Pneumoniae in Brain Tissue
por: Wippel, Carolin, et al.
Publicado: (2011)

Differences in virulence of pneumolysin and autolysin mutants constructed by insertion duplication mutagenesis and in-frame deletion in Streptococcus pneumoniae
por: Liu, Esther Yip-Mei, et al.
Publicado: (2014)

Truncated Pneumolysin from Streptococcus pneumoniae as a TLR4-Antagonizing New Drug for Chronic Inflammatory Conditions
por: Chang, Shun-Fu, et al.
Publicado: (2020)

Efficacy and safety of Tuina for treatment of pediatric recurrent respiratory tract infections: A protocol for systematic review and meta-analysis
por: Tian, Ye, et al.
Publicado: (2021)

The Effectiveness of Wogonin on Treating Cough Mice With Mycoplasma Pneumoniae Infection
por: Liang, Mingchuan, et al.
Publicado: (2022)

Naturally-occurring serotype 3 Streptococcus pneumoniae strains that lack functional pneumolysin and autolysin have attenuated virulence but induce localized protective immune responses
por: Wong, Ηαnnah E., et al.
Publicado: (2023)

Mouse, but Not Human, ApoB-100 Lipoprotein Cholesterol Is a Potent Innate Inhibitor of Streptococcus pneumoniae Pneumolysin
por: Wade, Kristin R., et al.
Publicado: (2014)

Surface Proteins and Pneumolysin of Encapsulated and Nonencapsulated Streptococcus pneumoniae Mediate Virulence in a Chinchilla Model of Otitis Media
por: Keller, Lance E., et al.
Publicado: (2016)

Rational Manipulation of mRNA Folding Free Energy Allows Rheostat Control of Pneumolysin Production by Streptococcus pneumoniae
por: Amaral, Fábio E., et al.
Publicado: (2015)

Insights into the Evolutionary Relationships of LytA Autolysin and Ply Pneumolysin-Like Genes in Streptococcus pneumoniae and Related Streptococci
por: Morales, María, et al.
Publicado: (2015)

Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis
por: Domon, Hisanori, et al.
Publicado: (2016)

Construction of a pneumolysin deficient mutant in streptococcus pneumoniae serotype 1 strain 519/43 and phenotypic characterisation
por: Terra, Vanessa S., et al.
Publicado: (2020)

Streptococcus pneumoniae Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4(+) T Cells via Pneumolysin
por: Paulikat, Antje D., et al.
Publicado: (2022)

Engineering the specificity of Streptococcus pyogenes sortase A by loop grafting
por: Wójcik, Magdalena, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_sr9mipatmndoof93ovttv5id9i