Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS(1))

Nuclear magnetic resonance (NMR) studies have revealed that fast methyl sidechain dynamics can report on entropically-driven allostery. Yet, NMR applications have been largely limited to the super-microsecond motional regimes of G protein-coupled receptors (GPCRs). We use (13)C(ε)-methionine chemica...

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Detalles Bibliográficos
Autores principales: Bumbak, Fabian, Pons, Miquel, Inoue, Asuka, Paniagua, Juan Carlos, Yan, Fei, Wu, Hongwei, Robson, Scott A., Bathgate, Ross A.D., Scott, Daniel J., Gooley, Paul R., Ziarek, Joshua J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930568/
https://www.ncbi.nlm.nih.gov/pubmed/36680775
http://dx.doi.org/10.1016/j.celrep.2023.112015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930568/
https://www.ncbi.nlm.nih.gov/pubmed/36680775
http://dx.doi.org/10.1016/j.celrep.2023.112015

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