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Dieting reverses histone methylation and hypothalamic AgRP regulation in obese rats

INTRODUCTION: Although dieting is a key factor in improving physiological functions associated with obesity, the role by which histone methylation modulates satiety/hunger regulation of the hypothalamus through weight loss remains largely elusive. Canonically, H3K9me2 is a transcriptional repressive...

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Detalles Bibliográficos
Autores principales: Rapps, Kayla, Kisliouk, Tatiana, Marco, Asaf, Weller, Aron, Meiri, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9930686/
https://www.ncbi.nlm.nih.gov/pubmed/36817590
http://dx.doi.org/10.3389/fendo.2023.1121829