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Repurposing Lansoprazole and Posaconazole to treat leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action

Leishmaniasis remains a serious public health problem in many tropical regions of the world. Among neglected tropical diseases, the mortality rate of leishmaniasis is second only to malaria. All currently approved therapeutics have toxic side effects and face rapidly increasing resistance. To identi...

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Detalles Bibliográficos
Autores principales: Gupta, Yash, Goicoechea, Steven, Romero, Jesus G., Mathur, Raman, Caulfield, Thomas R., Becker, Daniel P., Durvasula, Ravi, Kempaiah, Prakasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931003/
https://www.ncbi.nlm.nih.gov/pubmed/35647721
http://dx.doi.org/10.38212/2224-6614.3394