Targeted proteomics using stable isotope labeled protein fragments enables precise and robust determination of total apolipoprotein(a) in human plasma

Lipoprotein(a), also known as Lp(a), is an LDL-like particle composed of apolipoprotein(a) (apo(a)) bound covalently to apolipoprotein B100. Plasma concentrations of Lp(a) are highly heritable and vary widely between individuals. Elevated plasma concentration of Lp(a) is considered as an independent...

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Detalles Bibliográficos
Autores principales: Hober, Andreas, Rekanovic, Mirela, Forsström, Björn, Hansson, Sara, Kotol, David, Percy, Andrew J., Uhlén, Mathias, Oscarsson, Jan, Edfors, Fredrik, Miliotis, Tasso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931122/
https://www.ncbi.nlm.nih.gov/pubmed/36791076
http://dx.doi.org/10.1371/journal.pone.0281772

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