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p57(Kip2) is an essential regulator of vitamin D receptor-dependent mechanisms

A cyclin-dependent kinase (CDK) inhibitor, p57(Kip2), is an important molecule involved in bone development; p57(Kip2)-deficient (p57-/-) mice display neonatal lethality resulting from abnormal bone formation and cleft palate. The modulator 1α,25-dihydroxyvitamin D(3) (l,25-(OH)(2)VD(3)) has shown t...

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Detalles Bibliográficos
Autores principales: Takahashi, Katsuhiko, Amano, Hitoshi, Urano, Tomohiko, Li, Minqi, Oki, Meiko, Aoki, Kazuhiro, Amizuka, Norio, Nakayama, Keiichi I., Nakayama, Keiko, Udagawa, Nobuyuki, Higashi, Nobuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931147/
https://www.ncbi.nlm.nih.gov/pubmed/36791055
http://dx.doi.org/10.1371/journal.pone.0276838