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Autolysosomal activation combined with lysosomal destabilization efficiently targets myeloid leukemia cells for cell death

INTRODUCTION: Current cancer research has led to a renewed interest in exploring lysosomal membrane permeabilization and lysosomal cell death as a targeted therapeutic approach for cancer treatment. Evidence suggests that differences in lysosomal biogenesis between cancer and normal cells might open...

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Detalles Bibliográficos
Autores principales: Shah, Harshit, Stankov, Metodi, Panayotova-Dimitrova, Diana, Yazdi, Amir, Budida, Ramachandramouli, Klusmann, Jan-Henning, Behrens, Georg M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931186/
https://www.ncbi.nlm.nih.gov/pubmed/36816923
http://dx.doi.org/10.3389/fonc.2023.999738

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