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Association of the risk factor UNC13A with survival and upper motor neuron involvement in amyotrophic lateral sclerosis

BACKGROUND: The UNC13A gene is an established susceptibility locus for amyotrophic lateral sclerosis (ALS) and a determinant of shorter survival after disease onset, with up to 33.0 months difference in life expectancy for carriers of the rs12608932 risk genotype. However, its overall effect on othe...

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Detalles Bibliográficos
Autores principales:	Manini, Arianna, Casiraghi, Valeria, Brusati, Alberto, Maranzano, Alessio, Gentile, Francesco, Colombo, Eleonora, Bonetti, Ruggero, Peverelli, Silvia, Invernizzi, Sabrina, Gentilini, Davide, Messina, Stefano, Verde, Federico, Poletti, Barbara, Fogh, Isabella, Morelli, Claudia, Silani, Vincenzo, Ratti, Antonia, Ticozzi, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931189/ https://www.ncbi.nlm.nih.gov/pubmed/36819716 http://dx.doi.org/10.3389/fnagi.2023.1067954

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