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TCR-engineered T cell therapy in solid tumors: State of the art and perspectives

T cell engineering has changed the landscape of cancer immunotherapy. Chimeric antigen receptor T cells have demonstrated a remarkable efficacy in the treatment of B cell malignancies in hematology. However, their clinical impact on solid tumors has been modest so far. T cells expressing an engineer...

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Detalles Bibliográficos
Autores principales:	Baulu, Estelle, Gardet, Célia, Chuvin, Nicolas, Depil, Stéphane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931212/ https://www.ncbi.nlm.nih.gov/pubmed/36791198 http://dx.doi.org/10.1126/sciadv.adf3700

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