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Phase separation of an actin nucleator by junctional microtubules regulates epithelial function

Liquid-liquid phase separation (LLPS) is involved in various dynamic biological phenomena. In epithelial cells, dynamic regulation of junctional actin filaments tethered to the apical junctional complex (AJC) is critical for maintaining internal homeostasis against external perturbations; however, t...

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Detalles Bibliográficos
Autores principales: Tsukita, Kazuto, Kitamata, Manabu, Kashihara, Hiroka, Yano, Tomoki, Fujiwara, Ikuko, Day, Timothy F., Katsuno, Tatsuya, Kim, Jaewon, Takenaga, Fumiko, Tanaka, Hiroo, Park, Sungsu, Miyata, Makoto, Watanabe, Hitomi, Kondoh, Gen, Takahashi, Ryosuke, Tamura, Atsushi, Tsukita, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931218/
https://www.ncbi.nlm.nih.gov/pubmed/36791197
http://dx.doi.org/10.1126/sciadv.adf6358