Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species

RAS-ERK (extracellular signal–regulated kinase) pathway signals are modulated by scaffold proteins that assemble the components of different kinase tiers into a sequential phosphorylation cascade. In the prevailing model scaffold proteins function as isolated entities, where the flux of phosphorylat...

Descripción completa

Detalles Bibliográficos
Autores principales: Martín-Vega, Ana, Ruiz-Peinado, Laura, García-Gómez, Rocío, Herrero, Ana, de la Fuente-Vivas, Dalia, Parvathaneni, Swetha, Caloto, Rubén, Morante, Marta, von Kriegsheim, Alex, Bustelo, Xosé R., Sacks, David B., Casar, Berta, Crespo, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931222/
https://www.ncbi.nlm.nih.gov/pubmed/36791195
http://dx.doi.org/10.1126/sciadv.add7969

Ejemplares similares

Ejemplares similares