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Understanding the impact of digital contact tracing during the COVID-19 pandemic

Digital contact tracing (DCT) applications have been introduced in many countries to aid the containment of COVID-19 outbreaks. Initially, enthusiasm was high regarding their implementation as a non-pharmaceutical intervention (NPI). However, no country was able to prevent larger outbreaks without f...

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Detalles Bibliográficos
Autores principales: Burdinski, Angelique, Brockmann, Dirk, Maier, Benjamin Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931320/
https://www.ncbi.nlm.nih.gov/pubmed/36812611
http://dx.doi.org/10.1371/journal.pdig.0000149
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author Burdinski, Angelique
Brockmann, Dirk
Maier, Benjamin Frank
author_facet Burdinski, Angelique
Brockmann, Dirk
Maier, Benjamin Frank
author_sort Burdinski, Angelique
collection PubMed
description Digital contact tracing (DCT) applications have been introduced in many countries to aid the containment of COVID-19 outbreaks. Initially, enthusiasm was high regarding their implementation as a non-pharmaceutical intervention (NPI). However, no country was able to prevent larger outbreaks without falling back to harsher NPIs. Here, we discuss results of a stochastic infectious-disease model that provide insights in how the progression of an outbreak and key parameters such as detection probability, app participation and its distribution, as well as engagement of users impact DCT efficacy informed by results of empirical studies. We further show how contact heterogeneity and local contact clustering impact the intervention’s efficacy. We conclude that DCT apps might have prevented cases on the order of single-digit percentages during single outbreaks for empirically plausible ranges of parameters, ignoring that a substantial part of these contacts would have been identified by manual contact tracing. This result is generally robust against changes in network topology with exceptions for homogeneous-degree, locally-clustered contact networks, on which the intervention prevents more infections. An improvement of efficacy is similarly observed when app participation is highly clustered. We find that DCT typically averts more cases during the super-critical phase of an epidemic when case counts are rising and the measured efficacy therefore depends on the time of evaluation.
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spelling pubmed-99313202023-02-16 Understanding the impact of digital contact tracing during the COVID-19 pandemic Burdinski, Angelique Brockmann, Dirk Maier, Benjamin Frank PLOS Digit Health Research Article Digital contact tracing (DCT) applications have been introduced in many countries to aid the containment of COVID-19 outbreaks. Initially, enthusiasm was high regarding their implementation as a non-pharmaceutical intervention (NPI). However, no country was able to prevent larger outbreaks without falling back to harsher NPIs. Here, we discuss results of a stochastic infectious-disease model that provide insights in how the progression of an outbreak and key parameters such as detection probability, app participation and its distribution, as well as engagement of users impact DCT efficacy informed by results of empirical studies. We further show how contact heterogeneity and local contact clustering impact the intervention’s efficacy. We conclude that DCT apps might have prevented cases on the order of single-digit percentages during single outbreaks for empirically plausible ranges of parameters, ignoring that a substantial part of these contacts would have been identified by manual contact tracing. This result is generally robust against changes in network topology with exceptions for homogeneous-degree, locally-clustered contact networks, on which the intervention prevents more infections. An improvement of efficacy is similarly observed when app participation is highly clustered. We find that DCT typically averts more cases during the super-critical phase of an epidemic when case counts are rising and the measured efficacy therefore depends on the time of evaluation. Public Library of Science 2022-12-06 /pmc/articles/PMC9931320/ /pubmed/36812611 http://dx.doi.org/10.1371/journal.pdig.0000149 Text en © 2022 Burdinski et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Burdinski, Angelique
Brockmann, Dirk
Maier, Benjamin Frank
Understanding the impact of digital contact tracing during the COVID-19 pandemic
title Understanding the impact of digital contact tracing during the COVID-19 pandemic
title_full Understanding the impact of digital contact tracing during the COVID-19 pandemic
title_fullStr Understanding the impact of digital contact tracing during the COVID-19 pandemic
title_full_unstemmed Understanding the impact of digital contact tracing during the COVID-19 pandemic
title_short Understanding the impact of digital contact tracing during the COVID-19 pandemic
title_sort understanding the impact of digital contact tracing during the covid-19 pandemic
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931320/
https://www.ncbi.nlm.nih.gov/pubmed/36812611
http://dx.doi.org/10.1371/journal.pdig.0000149
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