Disease trajectory of SLE clinical endpoints and covariates affecting disease severity and probability of response: Analysis of pooled patient‐level placebo (Standard‐of‐Care) data to enable model‐informed drug development

Systemic lupus erythematosus (SLE) is an autoimmune disease affecting multiple organ systems. Many investigational agents have failed or shown only modest effects when added to standard of care (SoC) therapy in placebo‐controlled trials, and only two therapies have been approved for SLE in the last...

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Detalles Bibliográficos
Autores principales: Goteti, Kosalaram, French, Jonathan, Garcia, Ramon, Li, Ying, Casset‐Semanaz, Florence, Aydemir, Aida, Townsend, Robert, Mateo, Cristina Vazquez, Studham, Matthew, Guenther, Oliver, Kao, Amy, Gastonguay, Marc, Girard, Pascal, Benincosa, Lisa, Venkatakrishnan, Karthik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931431/
https://www.ncbi.nlm.nih.gov/pubmed/36350330
http://dx.doi.org/10.1002/psp4.12888

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