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Oncolytic viral kinetics mechanistic modeling of Talimogene Laherparepvec (T‐VEC) a first‐in‐class oncolytic viral therapy in patients with advanced melanoma

Talimogene Laherparepvec (T‐VEC) is a first‐in‐class oncolytic virotherapy approved for the treatment of unresectable melanoma recurrent after initial surgery. Biodistribution data from a phase II study was used to develop a viral kinetic mechanistic model describing the interaction between cytokine...

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Detalles Bibliográficos
Autores principales:	Ahamadi, Malidi, Kast, Johannes, Chen, Po‐Wei, Huang, Xiaojun, Dutta, Sandeep, Upreti, Vijay V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931434/ https://www.ncbi.nlm.nih.gov/pubmed/36564918 http://dx.doi.org/10.1002/psp4.12898

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