Scalable in situ single-cell profiling by electrophoretic capture of mRNA using EEL FISH

Methods to spatially profile the transcriptome are dominated by a trade-off between resolution and throughput. Here we develop a method named Enhanced ELectric Fluorescence in situ Hybridization (EEL FISH) that can rapidly process large tissue samples without compromising spatial resolution. By elec...

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Detalles Bibliográficos
Autores principales: Borm, Lars E., Mossi Albiach, Alejandro, Mannens, Camiel C. A., Janusauskas, Jokubas, Özgün, Ceren, Fernández-García, David, Hodge, Rebecca, Castillo, Francisca, Hedin, Charlotte R. H., Villablanca, Eduardo J., Uhlén, Per, Lein, Ed S., Codeluppi, Simone, Linnarsson, Sten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931581/
https://www.ncbi.nlm.nih.gov/pubmed/36138169
http://dx.doi.org/10.1038/s41587-022-01455-3

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