Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins

Targeted degradation of cell surface and extracellular proteins via lysosomal delivery is an important means to modulate extracellular biology. However, these approaches have limitations due to lack of modularity, ease of development, restricted tissue targeting and applicability to both cell surfac...

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Detalles Bibliográficos
Autores principales: Pance, Katarina, Gramespacher, Josef A., Byrnes, James R., Salangsang, Fernando, Serrano, Juan-Antonio C., Cotton, Adam D., Steri, Veronica, Wells, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931583/
https://www.ncbi.nlm.nih.gov/pubmed/36138170
http://dx.doi.org/10.1038/s41587-022-01456-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931583/
https://www.ncbi.nlm.nih.gov/pubmed/36138170
http://dx.doi.org/10.1038/s41587-022-01456-2

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