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Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins
Targeted degradation of cell surface and extracellular proteins via lysosomal delivery is an important means to modulate extracellular biology. However, these approaches have limitations due to lack of modularity, ease of development, restricted tissue targeting and applicability to both cell surfac...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931583/ https://www.ncbi.nlm.nih.gov/pubmed/36138170 http://dx.doi.org/10.1038/s41587-022-01456-2 |