Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report

Primary neuroendocrine tumor (NET) of bladder is rare. It has four subtypes, and large cell neuroendocrine carcinoma (LCNEC) is the rarest. LCNEC affects mostly men over 60. Most common symptom is gross hematuria. It has no specific treatment. Metastasis is common and once occurred, average survival...

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Autores principales: Mahmoudnejad, Nastaran, Mohammadi Torbati, Peyman, Lashay, Alireza, Ahmadi, Navid, Guitynavard, Fateme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931890/
https://www.ncbi.nlm.nih.gov/pubmed/36816609
http://dx.doi.org/10.1016/j.eucr.2023.102347
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author Mahmoudnejad, Nastaran
Mohammadi Torbati, Peyman
Lashay, Alireza
Ahmadi, Navid
Guitynavard, Fateme
author_facet Mahmoudnejad, Nastaran
Mohammadi Torbati, Peyman
Lashay, Alireza
Ahmadi, Navid
Guitynavard, Fateme
author_sort Mahmoudnejad, Nastaran
collection PubMed
description Primary neuroendocrine tumor (NET) of bladder is rare. It has four subtypes, and large cell neuroendocrine carcinoma (LCNEC) is the rarest. LCNEC affects mostly men over 60. Most common symptom is gross hematuria. It has no specific treatment. Metastasis is common and once occurred, average survival would be less than three months. Herein we present diagnostic and therapeutic management of a 65-year-old female with LCNEC of bladder and concurrent high-grade urothelial carcinoma. Despite developing early liver metastasis, she achieved a one-year tumor-free survival.
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spelling pubmed-99318902023-02-17 Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report Mahmoudnejad, Nastaran Mohammadi Torbati, Peyman Lashay, Alireza Ahmadi, Navid Guitynavard, Fateme Urol Case Rep Oncology Primary neuroendocrine tumor (NET) of bladder is rare. It has four subtypes, and large cell neuroendocrine carcinoma (LCNEC) is the rarest. LCNEC affects mostly men over 60. Most common symptom is gross hematuria. It has no specific treatment. Metastasis is common and once occurred, average survival would be less than three months. Herein we present diagnostic and therapeutic management of a 65-year-old female with LCNEC of bladder and concurrent high-grade urothelial carcinoma. Despite developing early liver metastasis, she achieved a one-year tumor-free survival. Elsevier 2023-02-02 /pmc/articles/PMC9931890/ /pubmed/36816609 http://dx.doi.org/10.1016/j.eucr.2023.102347 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Mahmoudnejad, Nastaran
Mohammadi Torbati, Peyman
Lashay, Alireza
Ahmadi, Navid
Guitynavard, Fateme
Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report
title Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report
title_full Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report
title_fullStr Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report
title_full_unstemmed Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report
title_short Achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report
title_sort achieving a one-year-tumor-free survival in a female with primary large cell neuroendocrine carcinoma of the urinary bladder and liver metastasis; a case report
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9931890/
https://www.ncbi.nlm.nih.gov/pubmed/36816609
http://dx.doi.org/10.1016/j.eucr.2023.102347
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